Breast and Ovarian Cancer Screening Tests
Personalised test to assess predisposition risk
Womanfocus Genetic Screening Test
For women aged 25+
Test results in 7 working days
Identify cancer risk
The Womanfocus genetic cancer test accurately calculates the risk of a person developing breast and ovarian cancer during their lifetime, using a single saliva sample.
- If aged 25+
- Your mother or sister has had breast or ovarian cancer
- Or there is a strong history of cancer in the family
Breast and Ovarian Cancer is the Most Common Cancer in Women
48,000 new breast cancer cases in the Dubai annually
12,000 die from breast cancer annually
7,500 new ovarian cancer cases in the Dubai every year
4,100 die from ovarian cancer annually
Breast cancer is the most common cancer in women and Ovarian cancer is the most common gynaecological malignancy.
Family history and genetic factors are major risk factors in the development of breast and ovarian cancer.
Other risk factors include:
- advancing age
- being overweight
- hormonal and reproductive factors
- smoking history
- ethnic background
Family history is not enough. Test everyone and you overlook no one
Mutated genes involved in DNA repair called DNA Damage Repair (DDR) genes are associated with high or moderate risk of a person developing breast cancer. High risk genes such as BRCA1, BRCA2, PALB2 and STK11 genes are associated with a 40-90% lifetime risk of developing breast cancer. Similarly BRCA1 and BRCA2 genes are associated with a 30-50% and 10-25% risk of ovarian cancer development during a person’s lifetime.
Breast and ovarian cancer risk can also be increased by the inheritance of common genetic mutations called single nucleotide polymorphisms (SNPs). Individually a single SNP causes a very small increase in risk but cumulatively inheritance of many SNPs can give a lifetime breast cancer risk of 33%.
Those women identified at high risk can benefit from lifestyle changes, cancer preventative drugs and increased screenings to catch potential cancers at an early and treatable stage.
Customer requests a pre-test consultation with a Healthcare Provider
Order Womanfocus directly from the Healthcare Provider
Collect saliva sample as per instructions.
CellDig receives the sample and performs the test.
Customer receives results via a follow up consultation with Healthcare Provider
A loss of the balance of control between cell growth, division and cell death caused by changes in genes. Genes are a series of messages coded by our DNA that help to build and maintain the body.
Yes, all tumours are caused by gene changes meaning the balance of cell growth, division and death is lost.
No, familial factors are thought to be responsible for about 20% of tumours.
Age and gender are the two biggest factors followed by oestrogen exposure, genetics and family history. Oestrogen exposure includes the combined oral contraceptive pill and hormone replacement therapy. Please do not change any preparation until you have spoken to your family doctor.
To identify a gene change that might increase your risk of breast cancer that might mean lifestyle changes, a cancer preventative drug, screening or preventative testing may be offered.
This is likely to lower your risk of breast cancer but if you have a positive family history of breast cancer then additional screening from 40 onwards may still be offered.
Your risk of developing breast cancer can be calculated by either comparing with other people with the same gene change or through computer modelling that also takes into consideration other risk factors and your family history. Then you can be offered advice on risk reduction or early detection strategies.
The vast majority of these are part of the normal variation of life and are assessed using an internationally agreed code of practice (ACMG). If one of these variants are identified, these will be regularly re-assessed and you will be informed if the classification of the variant changes due to new information coming to light from laboratory research or other families being reported.
Maintaining body mass index in the normal range, reducing alcohol consumption and the use of hormonal blockers such as tamoxifen or aromatase inhibitors (after the menopause). In individuals with approximately a 1% per year risk of developing breast cancer, preventative surgery may sometimes be appropriate with psychological support and further discussion with peer patient champions.